J Mark Wilkinson Selected Research

Arthroplasty

5/2022	Revision and 90-day mortality following hip arthroplasty in patients with inflammatory arthritis and ankylosing spondylitis enrolled in the National Joint Registry for England and Wales.
3/2022	The risk of all-cause mortality, heart outcomes, cancer, and neurodegenerative disorders with cobalt-chrome-containing total hip arthroplasty implants : an analysis of the National Joint Registry.
11/2020	Personalized estimation of one-year mortality risk after elective hip or knee arthroplasty for osteoarthritis.
1/2019	The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA?
1/2013	A TNF variant that associates with susceptibility to musculoskeletal disease modulates thyroid hormone receptor binding to control promoter activation.
7/2011	Bisphosphonates in orthopedic applications.

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J Mark Wilkinson Research Topics

Disease

10	Osteolysis 01/2020 - 07/2003
9	Osteoarthritis 03/2022 - 01/2013
3	Arthritis (Polyarthritis) 05/2022 - 04/2012
3	Neoplasms (Cancer) 03/2022 - 01/2019
2	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 03/2022 - 01/2022
2	Heart Failure 03/2022 - 01/2022
2	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2022 - 01/2022
2	Infections 11/2021 - 02/2006
2	Pain (Aches) 01/2020 - 09/2011
2	Prosthesis Failure 01/2020 - 11/2015
2	Neoplasm Metastasis (Metastasis) 11/2019 - 01/2019
2	Breast Neoplasms (Breast Cancer) 11/2019 - 01/2019
2	Inflammation (Inflammations) 10/2015 - 01/2008
1	Ankylosing Spondylitis 05/2022
1	Hip Osteoarthritis (Coxarthrosis) 05/2022
1	Joint Diseases (Joint Disease) 01/2022
1	Myocardial Infarction 11/2021
1	Venous Thromboembolism 11/2021
1	Chronic Disease (Chronic Diseases) 01/2021
1	Reflex Sympathetic Dystrophy (Reflex Sympathetic Dystrophy Syndrome) 01/2020
1	Osteoporotic Fractures 01/2020
1	Osteophyte 01/2018
1	Disease Progression 01/2017
1	Cerebral Palsy (Spastic Diplegia) 01/2016
1	Experimental Arthritis 10/2015
1	Rheumatoid Arthritis 10/2015
1	Musculoskeletal Diseases (Musculoskeletal Disease) 01/2013
1	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 01/2013
1	Osteonecrosis (Kienbock's Disease) 07/2011
1	Bone Resorption 07/2003
1	Heterotopic Ossification (Ectopic Ossification) 05/2003

Drug/Important Bio-Agent (IBA)

3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2019 - 10/2008
3	CytokinesIBA 02/2016 - 04/2012
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013 - 11/2003
3	Interleukin-1 (Interleukin 1)IBA 04/2012 - 01/2008
2	3,5-tetrahydroaldosterone sulfate (THAS)IBA 03/2022 - 01/2022
2	CobaltIBA 03/2022 - 01/2022
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2018
2	CollagenIBA 10/2021 - 01/2017
2	Pharmaceutical PreparationsIBA 01/2021 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 05/2003
2	Interleukin-6 (Interleukin 6)IBA 12/2009 - 10/2008
1	Long Noncoding RNAIBA 01/2022
1	IntegrinsIBA 01/2022
1	Proteoglycans (Proteoglycan)IBA 01/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2022
1	Diphosphonates (Bisphosphonates)IBA 01/2020
1	Proteins (Proteins, Gene)FDA Link 11/2019
1	LuciferasesIBA 11/2019
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2019
1	Cadherins (E-Cadherin)IBA 01/2019
1	canakinumab FDA Link 01/2019
1	CateninsIBA 01/2019
1	TitaniumIBA 02/2016
1	Pathogen-Associated Molecular Pattern MoleculesIBA 02/2016
1	Biological ProductsIBA 02/2016
1	Histone Deacetylases (Histone Deacetylase)IBA 10/2015
1	EnzymesIBA 10/2015
1	Histone Deacetylase 1IBA 10/2015
1	Small Interfering RNA (siRNA)IBA 10/2015
1	Mitochondrial DNA (mtDNA)IBA 01/2013
1	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 01/2013
1	Matrix Metalloproteinases (MMPs)IBA 04/2012
1	ProstaglandinsIBA 04/2012
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2012
1	Peptide Hydrolases (Proteases)FDA Link 04/2012
1	CannabinoidsIBA 04/2012
1	Nerve Growth Factor (NGF)IBA 09/2011
1	Monoclonal AntibodiesIBA 09/2011
1	Messenger RNA (mRNA)IBA 10/2008
1	Polyethylene (Polythene)IBA 05/2005
1	Collagen Type I (Type I Collagen)IBA 07/2003

Therapy/Procedure

11	Hip Replacement Arthroplasty (Total Hip Replacement) 03/2022 - 05/2003
6	Arthroplasty 05/2022 - 07/2011
4	Therapeutics 01/2022 - 07/2003
3	Reoperation 01/2019 - 02/2006
2	Replacement Arthroplasty 01/2022 - 01/2020
2	Knee Replacement Arthroplasty (Total Knee Replacement) 11/2021 - 11/2020
1	Secondary Prevention 01/2020
1	Prostheses and Implants (Prosthesis) 01/2019
1	Bone Transplantation (Bone Grafting) 07/2011